Malignant acanthosis nigricans as a paraneoplastic manifestation of metastatic breast cancer

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Acanthosis Nigricans – a Clinical Manifestation of a Gastric Cancer

Diffuse cutaneous hyperpigmentation may have various causes: endocrine, metabolic, autoimmune, melanosis secondary to metastatic melanoma, drug or heavy metal poisoning. A cause to remember is acanthosis nigricans, which, in the form of paraneoplastic syndrome may be the first or even the only clinical manifestation of a cancer. The most common cause of malignant acanthosis nigricans is the gas...

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Malignant Acanthosis Nigricans Associated with Ovarian Cancer

Malignant acanthosis nigricans is a cutaneous eruption characterized by symmetric hyperpigmented hyperkeratosis, dermal papillomatosis, and mucosal involvement associated with internal malignancies. Tripe palms refers to a characteristic velvety thickening of the palms, with exaggeration of normal skin markings. We present the second case of ovarian cancer in association with two coexisting par...

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Acanthosis nigricans and "tripe palm" as paraneoplastic manifestations of metastatic tumor.

Acanthosis nigricans is a common dermatosis and is most often associated with benign conditions, such as insulin resistance. It is rare as a paraneoplastic marker. As such, it is characterized by sudden onset and rapid dissemination of velvety and hyperchromic skin lesions. The term "tripe palm" refers to exaggeration of the palmar ridge pattern, which resembles the internal surface of the bovi...

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A case of acanthosis nigricans as a paraneoplastic syndrome with squamous cell lung cancer

A 55-year-old man presented with oral mucosal ulcers, blackening of both hands, and hyperpigmentation on axillary, anal, and inguinal regions for the last 3 months, which were all progressive. The patient was referred to the oncology department with the diagnosis of acanthosis nigricans for investigation of an underlying malignancy. He was a smoker. A computed tomography scan of thorax revealed...

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Malignant acanthosis nigricans associated with prostate cancer: a case report

BACKGROUND Acanthosis nigricans is characterized by hyperpigmentation and hyperkeratosis of the skin or mucous membranes. Its malignant form is associated with internal neoplasms, especially gastric adenocarcinoma (55-61%). Coexistence with prostate cancer is uncommon. In the paraneoplastic type of this dermatosis, the skin and mucous lesions are characteristically of more sudden onset and more...

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ژورنال

عنوان ژورنال: International Journal of Women's Dermatology

سال: 2019

ISSN: 2352-6475

DOI: 10.1016/j.ijwd.2019.03.002